AMA endorses SG’s advisory on OD-reversing drug naloxone

The American Medical Association released the following statement on April 5…

The U.S. Surgeon General this morning urged more Americans to carry naloxone to help save lives from overdose. The American Medical Association strongly endorses the Surgeon General’s advisory on naloxone (see the full Surgeon General advisory and AMA statement below). The AMA Opioid Task Force has encouraged physicians to co-prescribe naloxone for all patients at risk of overdose, and has collected naloxone-specific resources on the AMA opioid microsite, including specific guidance to help physicians.

Surgeon General releases advisory on naloxone, an opioid overdose-reversing drug

Today, U.S. Surgeon General Jerome M. Adams, M.D., M.P.H., urged more Americans to carry a lifesaving medication that can reverse the effects of an opioid overdose.

The medication, naloxone, is already carried by many first responders, such as EMTs and police officers. The Surgeon General is now recommending that more individuals, including family, friends and those who are personally at risk for an opioid overdose, also keep the drug on hand.

An estimated 2.1 million people in the U.S. struggle with an opioid use disorder. Rates of opioid overdose deaths are rapidly increasing. Since 2010, the number of opioid overdose deaths has doubled from more than 21,000 to more than 42,000 in 2016, with the sharpest increase occurring among deaths related to illicitly made fentanyl and fentanyl analogs (synthetic opioids).

Opioids are a class of drugs that include medications, such as oxycodone, hydrocodone and methadone, which are commonly prescribed to treat pain. Pharmaceutical fentanyl is a synthetic opioid which is 50 times more potent than heroin and 100 times more potent than morphine. It is approved for treating severe pain, typically post-surgical or advanced cancer pain. However, most recent cases of fentanyl-related harms are a result of illicitly made fentanyl.

“Each day we lose 115 Americans to an opioid overdose – that’s one person every 12.5 minutes,” said Surgeon General Adams. “It is time to make sure more people have access to this lifesaving medication, because 77 percent of opioid overdose deaths occur outside of a medical setting and more than half occur at home.”

Naloxone, an FDA-approved medication that can be delivered via nasal mist or injection, is not a long-term solution, but it can temporarily suspend the effects of the overdose until emergency responders arrive.

“To manage opioid addiction and prevent future overdoses, increased naloxone availability must occur in conjunction with expanded access to evidence-based treatment for opioid use disorder,” the Surgeon General said.

All states have passed laws to increase access to naloxone and, in most states, you can walk into a pharmacy and request naloxone even if you don’t already have a prescription. In addition, most states have laws designed to protect health care professionals for prescribing and dispensing naloxone from civil and criminal liabilities as well as Good Samaritan laws to protect people who administer naloxone or call for help during an opioid overdose emergency.

Naloxone is covered by most insurance plans and, for those without coverage, may be available at low or no cost through local public health programs or through retailer and manufacturer discounts. It is easy to use, safe to administer and widely available.

Today’s Surgeon General advisory on naloxone is part of the administration’s ongoing effort to respond to the sharp increase among drug overdose deaths. Just last month, the Centers for Disease Control and Prevention released new data showing a rise in emergency department visits for opioid overdoses. From July 2016 through September 2017, opioid overdoses increased 30 percent in all parts of the U.S.

Expanding the use of the overdose-reversing drug naloxone is a key part of the public health response to the opioid crisis, along with effective prevention, treatment and recovery programs for opioid use disorder. Research shows a combination of medication, counseling and behavioral therapy, also known as Medication Assisted Treatment, or MAT, can help people achieve long-term recovery.

For more information on how to get help, call SAMHSA’s National Helpline at 800.662.HELP (4357) or go to https://www.findtreatment.samhsa.gov to find a treatment center.

To learn more about how individuals can recognize and respond to an opioid overdose, visit www.surgeongeneral.gov to read more.

AMA applauds Surgeon General’s call for expanded availability of naloxone

The following statement is attributable to Patrice A. Harris, M.D., MA, chair of the AMA Opioid Task Force…

“The American Medical Association strongly endorses the Surgeon General’s advisory on naloxone. The AMA Opioid Task Force has encouraged physicians to co-prescribe naloxone for all patients at risk of overdose. Surgeon General Adams, physicians, first responders and public health advocates all recognize that naloxone is a literal lifesaver and a vital tool in our fight against the opioid epidemic. Patients, family members and friends should not hesitate to ask their physicians to prescribe naloxone so they can save their own or their loved one’s lives. Many states have made naloxone available without a prescription. All forms of naloxone should be readily available and covered by insurance plans with minimal or no cost-sharing. The AMA looks forward to working closely with the Surgeon General’s Office to help bring an end to the epidemic of opioid overdose deaths.”

Click for Surgeon General advisory on naloxone

Click for AMA opioid microsite, including specific physician guidelines